SCHEMBL35318

SCHEMBL35318

O=c1cc(-c2ccc(O)c(O)c2)oc2c(O)c(O)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 14/20 1.00
BRD4 O60885 1/20 1.00
KDM4E B2RXH2 4/20 0.73
ALDH1A1 P00352 4/20 0.73
CYP3A4 P08684 4/20 0.73
MAPT P10636 4/20 0.73
HPGD P15428 4/20 0.73
ALOX15 P16050 4/20 0.73
HSD17B10 Q99714 4/20 0.73
MAPK1 P28482 3/20 0.73
TP53 P04637 2/20 0.73
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
SMN1; SMN2 Q16637 2/20 0.73
IKBKB O14920 1/20 0.73
CYP19A1 P11511 1/20 0.73
MAOA P21397 1/20 0.73
MAOB P27338 1/20 0.73
NTRK2 Q16620 1/20 0.73
CYP2C9 P11712 2/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6804531 0.89 TERT (0.81) TERTBRD4KDM4EALDH1A1CYP3A4
SCHEMBL6613794 0.88 TERT (0.79) TERTBRD4KDM4EALDH1A1CYP3A4
SCHEMBL31322174 0.88 TERT (1.00) TERTBRD4KDM4EALDH1A1CYP3A4
SCHEMBL4649959 0.88 TERT (1.00) TERTBRD4KDM4EALDH1A1CYP3A4
SCHEMBL6618692 0.87 TERT (0.76) TERTBRD4KDM4EALDH1A1CYP3A4
SCHEMBL6613071 0.85 TERT (1.00) TERTBRD4KDM4EALDH1A1CYP3A4
SCHEMBL6802693 0.85 TERT (0.74) TERTBRD4KDM4EALDH1A1CYP3A4
SCHEMBL6613454 0.85 TERT (1.00) TERTBRD4ALDH1A1CYP3A4MAPT
SCHEMBL6614126 0.85 TERT (1.00) TERTBRD4KDM4EALDH1A1CYP3A4
SCHEMBL6618127 0.85 TERT (0.78) TERTBRD4KDM4EALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250281560-A1 METHOD FOR PREVENTING AND/OR TREATING CANCER OR AUTOIMMUNE DISEASE WITH 3,4,2 Prime,3 Prime,4 Prime-PENTAHYDROXY-TRANS-CHALCONE NATIONAL CHUNG HSING UNIVERSITY (TW) 2025-09-11 US claimed
WO-2023150072-A1 COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER SINCLAIR DAVID A (US) 2023-08-10 WO claimed
US-20160367497-A1 METHODS AND COMPOSITIONS FOR TREATING NEUROPATHIES WASHINGTON UNIVERSITY 2016-12-22 US claimed
EP-2670404-A1 SIRTUIN MODULATORS AS VIRUS PRODUCTION MODULATORS The Trustees of Princeton University (US) 2013-12-11 EP claimed
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2013-07-25 US claimed
US-8414936-B2 Use of Acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2013-04-09 US claimed
WO-2012106509-A1 SIRTUIN MODULATORS AS VIRUS PRODUCTION MODULATORS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2012-08-09 WO claimed
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-12 US claimed
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2010-12-09 US claimed
US-20100047177-A1 METHODS AND COMPOSITIONS FOR TREATING NEUROPATHIES WASHINGTON UNIVERSITY (US) 2010-02-25 US claimed
US-20040242503-A1 Compositions comprising blockers of l-dopa renal cell transfer for the treatment of parkinson's disease ATTENTION LABS INCORPORATED 2004-12-02 US claimed
EP-1267853-B1 COMPOSITIONS COMPRISING BLOCKERS OF L-DOPA RENAL CELL TRANSFER FOR THE TREATMENT OF PARKINSON'S DISEASE PORTELA & CA SA (PT) 2004-09-08 EP claimed
EP-1435930-A2 ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-07-14 EP claimed
WO-2003032969-A2 ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2003-04-24 WO claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1267853-A2 COMPOSITIONS COMPRISING BLOCKERS OF L-DOPA RENAL CELL TRANSFER FOR THE TREATMENT OF PARKINSON'S DISEASE Portela & Ca., S.A. (PT) 2003-01-02 EP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
WO-2001068065-A9 COMPOSITIONS COMPRISING BLOCKERS OF L-DOPA RENAL CELL TRANSFER FOR THE TREATMENT OF PARKINSON'S DISEASE PORTELA & CA SA (PT) 2002-07-18 WO claimed
WO-2001068065-A2 COMPOSITIONS COMPRISING BLOCKERS OF L-DOPA RENAL CELL TRANSFER FOR THE TREATMENT OF PARKINSON'S DISEASE PORTELA & COMPANHIA S.A. (PT) 2001-09-20 WO claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, AOX1, ACACA TERT 2205/4885BRD4 4101/4885KDM4E 1981/4885
US-20040242503-A1 Compositions comprising blockers of l-dopa renal cell transfer for the treatment of parkinson's disease COMT, DDC, AADAT TERT 1828/4885BRD4 2867/4885KDM4E 976/4885
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, ACACA, ACAT1 TERT 2114/4885BRD4 3856/4885KDM4E 1895/4885
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, AOX1, ACACA TERT 2205/4885BRD4 4101/4885KDM4E 1981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.