Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HEXA | P06865 | 2/20 | 0.36 |
| ▸ | HEXB | P07686 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190064 | 0.85 | KEAP1 (0.38) | KEAP1SMN1; SMN2HEXAHEXBSIGMAR1 | |
| Hydrochloric Acid SCHEMBL8174495 | 0.83 | ITGB3 (0.44) | CYP2D6 | |
| SCHEMBL1446283 | 0.78 | KEAP1 (0.33) | KEAP1SMN1; SMN2SIGMAR1CYP2D6HSD17B10 | |
| SCHEMBL11670622 | 0.76 | — | — | |
| SCHEMBL880547 | 0.75 | ALOX15 (0.33) | ALOX15 | |
| Hydrochloric Acid SCHEMBL5488595 | 0.73 | GAA (0.36) | KEAP1SMN1; SMN2 | |
| SCHEMBL5587563 | 0.73 | ACE (0.31) | KEAP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL853595 | 0.73 | ALOX15 (0.32) | ALOX15 | |
| SCHEMBL1446364 | 0.73 | ALDH1A1 (0.42) | KEAP1SMN1; SMN2CYP2D6 | |
| SCHEMBL56994 | 0.73 | TSHR (0.50) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504628-A | Synthetic method of pleshafu impurity | 北京沣瑞医药科技有限公司 | 2025-02-25 | — | — | CN | disclosed |