Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.32 |
| ▸ | HEXB | P07686 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446283 | 0.87 | KEAP1 (0.33) | KEAP1SMN1; SMN2SIGMAR1CYP2D6HSD17B10 | |
| SCHEMBL31324973 | 0.85 | KEAP1 (0.38) | KEAP1SMN1; SMN2SIGMAR1CYP2D6HEXA | |
| SCHEMBL471725 | 0.84 | ALOX15 (0.41) | CYP2D6DRD3KCNH2ALOX15DRD2 | |
| SCHEMBL10850120 | 0.81 | MEN1 (0.39) | SMN1; SMN2BCHEACHEHSD17B10 | |
| SCHEMBL4873038 | 0.80 | DRD3 (0.60) | SIGMAR1CYP2D6DRD3KCNH2DRD2 | |
| SCHEMBL1446622 | 0.79 | PER2 (0.38) | KEAP1SMN1; SMN2 | |
| SCHEMBL10854804 | 0.79 | GBA1 (0.39) | BCHEACHE | |
| SCHEMBL24052007 | 0.79 | BCHE (0.33) | SIGMAR1BCHEACHE | |
| SCHEMBL10848072 | 0.78 | GBA1 (0.41) | BCHEACHE | |
| SCHEMBL10834524 | 0.76 | DRD2 (0.61) | CYP2D6DRD3KCNH2HTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
| EP-0463478-B1 | Reactive dyes having a triphendioxazin chromophor | BASF AG (DE) | 1995-12-13 | — | — | EP | disclosed |
| US-5194607-A | REACTIVE DYES WITH A TRIPHENDIOXAZINE CHROMOPHORE | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0463478-A2 | Reactive dyes having a triphendioxazin chromophor | BASF Aktiengesellschaft (DE) | 1992-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | KEAP1 634/4885SMN1; SMN2 3979/4885SIGMAR1 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.