Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.58 |
| ▸ | MMP12 | P39900 | 2/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991969 | 0.90 | ALDH1A1 (0.57) | FFAR1HDAC2HDAC1HDAC3HDAC4 | |
| SCHEMBL10197486 | 0.83 | LMNA (0.58) | FFAR1HDAC2HDAC1HDAC3HDAC4 | |
| SCHEMBL4827768 | 0.83 | FFAR1 (0.65) | FFAR1HDAC2HDAC1MMP12FFAR4 | |
| SCHEMBL480043 | 0.83 | FFAR1 (0.65) | FFAR1HDAC2HDAC1MMP12FFAR4 | |
| SCHEMBL28742807 | 0.80 | FFAR1 (0.71) | FFAR1HDAC2HDAC1HDAC3HDAC4 | |
| SCHEMBL7640251 | 0.79 | PLAAT3 (0.58) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL7060526 | 0.79 | PLAAT3 (0.61) | FFAR1HDAC2HDAC1HDAC3HDAC4 | |
| SCHEMBL7060208 | 0.79 | F2RL1 (0.69) | FFAR1PLAAT5PLAAT4PLAAT3PLAAT2 | |
| SCHEMBL7061791 | 0.79 | PLAAT3 (0.53) | FFAR1FFAR4PLAAT5PLAAT4PLAAT3 | |
| SCHEMBL20897266 | 0.78 | KEAP1 (0.55) | FFAR1HDAC2HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093427-B2 | Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-01-10 | — | — | US | disclosed |
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | CYP4F2, ACR, CYP4F3 | FFAR1 1407/4885HDAC2 3501/4885HDAC1 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.