Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31330313 | 1.00 | ADORA2A (0.33) | ADORA2AADORA2BADORA1GPR84CDK1 | |
| SCHEMBL5486374 | 0.74 | ADORA2B (0.42) | ADORA2AADORA2BALDH1A1 | |
| SCHEMBL31330327 | 0.70 | ADORA2A (0.33) | ADORA2AADORA2BADORA1GPR84 | |
| SCHEMBL31330324 | 0.68 | ADORA2A (0.33) | ADORA2AADORA2BADORA1 | |
| SCHEMBL31330320 | 0.64 | ADORA3 (0.32) | ADORA2BGPR84 | |
| SCHEMBL31330275 | 0.64 | ADORA2A (0.31) | ADORA2AADORA2BADORA1 | |
| SCHEMBL31330242 | 0.60 | ADORA2A (0.31) | ADORA2AADORA2BADORA1 | |
| SCHEMBL21457937 | 0.59 | GLS (0.50) | — | |
| SCHEMBL21457938 | 0.59 | GLS (0.50) | — | |
| SCHEMBL8916963 | 0.56 | NFE2L2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024249959-A1 | COMPOSITIONS REDUCING THE EXPRESSION OR ACTIVITY OF C1 GALT1 FOR TREATING EWING SARCOMA | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2024-12-05 | — | — | WO | disclosed |