Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | C1S | P09871 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333042 | 0.91 | CA5A (0.44) | CA5ATSHRMAPK1PTGDR2GRM2 | |
| SCHEMBL31333075 | 0.85 | MAPT (0.45) | PDE4AKDM4C | |
| SCHEMBL31333022 | 0.81 | ROCK2 (0.44) | GRM2KDM4CROCK2MAPK14 | |
| SCHEMBL9714155 | 0.79 | CA5A (0.47) | CA5AOPRM1OPRD1ADORA2AADORA1 | |
| SCHEMBL31333078 | 0.79 | GRM2 (0.47) | KCNH2GRM2HDAC1MAPK14 | |
| SCHEMBL31333083 | 0.78 | PPARG (0.40) | PTGDR2GRM2KDM4CMAPK14 | |
| SCHEMBL31333082 | 0.78 | ROCK2 (0.39) | C1SPTGDR2GRM2ROCK2 | |
| SCHEMBL31333058 | 0.77 | KDM5A (0.43) | — | |
| SCHEMBL9714294 | 0.77 | CA5A (0.48) | CA5AOPRM1OPRD1ADORA2AADORA1 | |
| SCHEMBL9714146 | 0.77 | CA5A (0.58) | CA5AOPRM1OPRD1GRM2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320386-A | METTL3 inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2025-01-17 | — | — | CN | disclosed |