Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333082 | 0.90 | ROCK2 (0.39) | PTGDR2GRM2MAPK8SLC29A1 | |
| SCHEMBL31333075 | 0.85 | MAPT (0.45) | PPARGKDM4EKDM4C | |
| SCHEMBL31333078 | 0.82 | GRM2 (0.47) | HDAC6KDM4ESMN1; SMN2GRM2MAPK14 | |
| SCHEMBL9714527 | 0.80 | GRM2 (0.43) | AURKARPS6KB1AURKBKDM4ESMN1; SMN2 | |
| SCHEMBL31333022 | 0.79 | ROCK2 (0.44) | SMN1; SMN2GRM2MAPK14KDM4C | |
| SCHEMBL31333084 | 0.78 | CA5A (0.52) | PTGDR2GRM2MAPK14KDM4C | |
| SCHEMBL31333065 | 0.76 | CYP2C19 (0.40) | KDM4ESLC29A1 | |
| SCHEMBL31333037 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2 | |
| SCHEMBL9714594 | 0.75 | GPBAR1 (0.55) | PPARGAURKARPS6KB1AURKBHDAC6 | |
| SCHEMBL31333054 | 0.74 | ALDH1A1 (0.47) | PPARGAURKARPS6KB1AURKBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320386-A | METTL3 inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2025-01-17 | — | — | CN | disclosed |