Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333078 | 0.85 | GRM2 (0.47) | MAPTSMN1; SMN2GRM2THRBMMP13 | |
| SCHEMBL31333025 | 0.84 | ALDH1A1 (0.51) | MAPTALDH1A1SMN1; SMN2MMP13PIK3CD | |
| SCHEMBL31333086 | 0.84 | ATM (0.51) | ROCK2ROCK1MAOBMAPTALDH1A1 | |
| SCHEMBL3524356 | 0.82 | HSD17B13 (0.47) | ROCK2ROCK1PDE1CMAPTALDH1A1 | |
| SCHEMBL31333084 | 0.81 | CA5A (0.52) | ROCK2GRM2KDM4CMAPK14 | |
| SCHEMBL31333074 | 0.81 | TP53 (0.53) | ROCK2ROCK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15965384 | 0.80 | KDM4C (0.57) | MAOBPARP10ALDH1A1SMN1; SMN2GRM2 | |
| SCHEMBL31333091 | 0.79 | ADRA1D (0.51) | ALDH1A1SMN1; SMN2HSD17B13MMP13CYP11B1 | |
| SCHEMBL7974168 | 0.79 | CDK9 (0.45) | ROCK2ROCK1MAOBPARP10MAPT | |
| SCHEMBL31333082 | 0.79 | ROCK2 (0.39) | ROCK2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320386-A | METTL3 inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2025-01-17 | — | — | CN | disclosed |