Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141851 | 0.78 | CAMKK2 (0.35) | NQO1PIN1CAMKK2SRCCTSB | |
| SCHEMBL3128146 | 0.78 | GRIN2D (0.35) | RAB9AMAPT | |
| SCHEMBL3140892 | 0.78 | HDAC6 (0.33) | HDAC6MAPT | |
| SCHEMBL2107950 | 0.78 | SMAD3 (0.45) | PIN1MAPTKMT2AAHR | |
| SCHEMBL3412763 | 0.77 | CYP19A1 (0.50) | PIN1CYP19A1 | |
| SCHEMBL3145657 | 0.75 | CHEK1 (0.38) | PIN1ENPP1 | |
| SCHEMBL3136953 | 0.75 | POLB (0.40) | ENPP1HDAC6MAPTKMT2A | |
| SCHEMBL3127269 | 0.74 | CHEK1 (0.37) | PIN1ENPP1 | |
| SCHEMBL15567755 | 0.73 | GABRP (0.39) | NPC1RAB9AMAPT | |
| SCHEMBL22533604 | 0.70 | NQO1 (0.44) | NQO1METMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636224-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE | PROSIDION LTD (GB) | 2010-07-14 | — | — | EP | claimed |