Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965749 | 0.87 | CHRM4 (0.50) | MAPTPOLBALDH1A1LMNASIGMAR1 | |
| SCHEMBL31335045 | 0.87 | TSHR (0.48) | MAPTALDH1A1GAACTSLCTSB | |
| SCHEMBL30135904 | 0.85 | SIGMAR1 (0.47) | MAPTPOLBALDH1A1GAACTSL | |
| SCHEMBL30135712 | 0.81 | MAPT (0.45) | MAPTPOLBALDH1A1GAACTSL | |
| SCHEMBL30136014 | 0.80 | POLB (0.42) | MAPTPOLBALDH1A1LMNABRD4 | |
| SCHEMBL30965765 | 0.80 | MAPT (0.44) | MAPTPOLBALDH1A1LMNABRD4 | |
| SCHEMBL31334686 | 0.77 | DDB1 (0.41) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL30915181 | 0.77 | DRD2 (0.54) | MAPTPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL13419542 | 0.77 | DRD2 (0.54) | MAPTPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL2089251 | 0.76 | KMT2A (0.57) | MAPTPOLBALDH1A1LMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |