Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134587 | 0.89 | KMT2A (0.47) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL13394864 | 0.83 | RAB9A (0.49) | RAB9AMAPTTSHRABL1RIN1 | |
| SCHEMBL3133587 | 0.82 | NPC1 (0.43) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL2153078 | 0.81 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL3130276 | 0.80 | ABL1 (0.64) | ALDH1A1RAB9ASMN1; SMN2MAPTABL1 | |
| SCHEMBL3136443 | 0.79 | ABL1 (0.53) | ALDH1A1RAB9ANPC1MAPTATM | |
| SCHEMBL3130187 | 0.75 | NAAA (0.44) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL4844713 | 0.74 | RAB9A (0.45) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL3130066 | 0.74 | NPC1 (0.45) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL3134598 | 0.73 | KMT2A (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2174936-B1 | PNA monomer and precursor | PANAGENE INC (KR) | 2013-09-04 | — | — | EP | disclosed |
| EP-2174936-B1 | PNA monomer and precursor | PANAGENE INC (KR) | 2013-09-04 | — | — | EP | disclosed |
| EP-2174936-A1 | PNA monomer and precursor | Panagene, Inc. (KR) | 2010-04-14 | — | — | EP | disclosed |
| EP-1501812-B1 | PNA MONOMER AND PRECURSOR | PANAGENE INC (KR) | 2009-12-30 | — | — | EP | disclosed |
| EP-1501812-B1 | PNA MONOMER AND PRECURSOR | PANAGENE INC (KR) | 2009-12-30 | — | — | EP | disclosed |
| EP-1651642-B1 | PNA MONOMER AND PRECURSOR | PANAGENE INC (KR) | 2009-11-04 | — | — | EP | disclosed |
| US-7411065-B2 | Peptide nucleic acid monomers: diphenylmethyl, benzyl, alkylthioalkyl, or phenylthioalkyl esters of N-(1-[4-(2-benzothiazolyl-, 2-benzoxazolyl-, 2-benzofuranyl- or 2-benzothiophenyl-sulfonyl)-3-piperazinon-1-ylcarbonylmethyl]pyrimidon-4-yl)carbamic acids | PANAGENE, INC. (KR) | 2008-08-12 | — | — | US | disclosed |
| US-7411065-B2 | Peptide nucleic acid monomers: diphenylmethyl, benzyl, alkylthioalkyl, or phenylthioalkyl esters of N-(1-[4-(2-benzothiazolyl-, 2-benzoxazolyl-, 2-benzofuranyl- or 2-benzothiophenyl-sulfonyl)-3-piperazinon-1-ylcarbonylmethyl]pyrimidon-4-yl)carbamic acids | PANAGENE, INC. (KR) | 2008-08-12 | — | — | US | disclosed |
| US-7371859-B2 | Peptide nucleic acid monomers; 1-(4-(benzothiazolyl-, benzoxazolyl-, benzofuranyl-, and benzothiophenyl- sulfonyl)piperidin-3-one-1-ylcarbonylmethyl)adenines; suitable for automatic and parallel synthesis; increased yields | PANAGENE, INC. (KR) | 2008-05-13 | — | — | US | disclosed |
| US-7371859-B2 | Peptide nucleic acid monomers; 1-(4-(benzothiazolyl-, benzoxazolyl-, benzofuranyl-, and benzothiophenyl- sulfonyl)piperidin-3-one-1-ylcarbonylmethyl)adenines; suitable for automatic and parallel synthesis; increased yields | PANAGENE, INC. (KR) | 2008-05-13 | — | — | US | disclosed |
| US-20060008835-A1 | PNA monomer and precursor | KIM SUNG K | 2006-01-12 | — | — | US | disclosed |
| US-20060003374-A1 | Method of making PNA oligomers | KIM SUNG K | 2006-01-05 | — | — | US | disclosed |
| US-20050283005-A1 | PNA monomer and precursor | KIM SUNG K | 2005-12-22 | — | — | US | disclosed |
| US-6969766-B2 | PNA monomer and precursor | PANAGENE, INC. (KR) | 2005-11-29 | — | — | US | disclosed |
| US-20050250785-A1 | PNA monomer and precursor | PANAGENE, INC. (KR) | 2005-11-10 | — | — | US | disclosed |
| US-20050250786-A1 | PNA monomer and precursor | PANAGENE, INC. (KR) | 2005-11-10 | — | — | US | disclosed |
| US-20050026930-A1 | PNA monomer and precursor | PANAGENE, INC. (KR) | 2005-02-03 | — | — | US | disclosed |
| EP-1501812-A1 | PNA MONOMER AND PRECURSOR | Panagene, Inc. (KR) | 2005-02-02 | — | — | EP | disclosed |
| US-20030225252-A1 | PNA monomer and precursor | PANAGENE, INC. (KR) | 2003-12-04 | — | — | US | disclosed |
| WO-2003091231-A1 | PNA MONOMER AND PRECURSOR | PANAGENE, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050283005-A1 | PNA monomer and precursor | PNISR, RNGTT, POLL | ALDH1A1 3966/4885RAB9A 3554/4885NPC1 2931/4885 |
| US-20050250785-A1 | PNA monomer and precursor | PNISR, RNGTT, POLL | ALDH1A1 3966/4885RAB9A 3554/4885NPC1 2931/4885 |
| US-20030225252-A1 | PNA monomer and precursor | PNISR, RNGTT, NCL | ALDH1A1 4151/4885RAB9A 3709/4885NPC1 3298/4885 |
| US-20050026930-A1 | PNA monomer and precursor | RNGTT, POLL, NSUN3 | ALDH1A1 3450/4885RAB9A 3664/4885NPC1 1888/4885 |
| US-20060008835-A1 | PNA monomer and precursor | PNISR, RNGTT, POLL | ALDH1A1 3966/4885RAB9A 3554/4885NPC1 2931/4885 |
| US-20050250786-A1 | PNA monomer and precursor | PNISR, RNGTT, NPR1 | ALDH1A1 3448/4885RAB9A 3805/4885NPC1 3187/4885 |
| US-20060003374-A1 | Method of making PNA oligomers | RNGTT, POLL, PNISR | ALDH1A1 4029/4885RAB9A 3626/4885NPC1 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.