Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 13/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 13/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 11/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25815441 | 0.89 | BAZ2B (0.53) | BAZ2BGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL31336826 | 0.78 | GABRG2 (0.36) | BAZ2BGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL27163039 | 0.72 | MEN1 (0.39) | KDM4ERAB9AKMT2AGRNSORT1 | |
| SCHEMBL2246566 | 0.69 | BAZ2B (0.62) | BAZ2BKDM4EGAARAB9AKMT2A | |
| SCHEMBL27166556 | 0.69 | LMNA (0.51) | KDM4EGAARAB9AKMT2A | |
| SCHEMBL27610277 | 0.68 | TSHR (0.49) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL30850118 | 0.67 | GABRG2 (0.38) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL25407400 | 0.67 | MAPK14 (0.46) | — | |
| SCHEMBL16450565 | 0.67 | ALDH1A1 (0.38) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL12868356 | 0.66 | BAZ2B (0.58) | BAZ2BKDM4EGAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |