SCHEMBL31337813

C[C@H](NC(=O)CNC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](N)COC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	GRB2	P62993	1/20	0.44

▸	OPRD1	P41143	9/20	0.41

▸	OPRM1	P35372	5/20	0.41

▸	BDKRB2	P30411	2/20	0.40

▸	CMA1	P23946	2/20	0.38

▸	ITGB3	P05106	2/20	0.38

▸	ITGA2B	P08514	2/20	0.38

▸	NTSR1	P30989	1/20	0.38

▸	APLNR	P35414	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31197912	0.98	GRB2 (0.44)	GRB2OPRD1OPRM1BDKRB2CMA1
SCHEMBL30744330	0.93	GRB2 (0.41)	GRB2OPRD1OPRM1BDKRB2APLNR
SCHEMBL30744292	0.92	APLNR (0.42)	GRB2OPRD1OPRM1CMA1ITGB3
SCHEMBL30543480	0.91	GRB2 (0.46)	GRB2OPRD1OPRM1BDKRB2NTSR1
SCHEMBL31197908	0.91	APLNR (0.44)	GRB2BDKRB2ITGB3ITGA2BNTSR1
SCHEMBL31197909	0.91	GRB2 (0.45)	GRB2CMA1ITGB3ITGA2BNTSR1
SCHEMBL29468832	0.89	GRB2 (0.46)	GRB2OPRD1OPRM1BDKRB2NTSR1
SCHEMBL30414346	0.89	GRB2 (0.42)	GRB2OPRD1OPRM1BDKRB2CMA1
SCHEMBL30423238	0.88	GRB2 (0.46)	GRB2OPRD1OPRM1BDKRB2
SCHEMBL30647290	0.87	OPRM1 (0.46)	GRB2OPRD1OPRM1BDKRB2CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-119080887-A	GLP-1/GIP double agonist and preparation method and application thereof	杭州中美华东制药有限公司	2024-12-06	—	—	CN	disclosed