SCHEMBL29468832

SCHEMBL29468832

C[C@H](NC(=O)CNC(=O)[C@@H](N)COC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GRB2 P62993 1/20 0.46
▸ NTSR1 P30989 5/20 0.43
▸ NTSR2 O95665 3/20 0.43
▸ F2 P00734 1/20 0.43
▸ OPRD1 P41143 5/20 0.41
▸ OPRM1 P35372 1/20 0.41
▸ BDKRB2 P30411 1/20 0.41
▸ SORT1 Q99523 1/20 0.40
▸ CXCR4 P61073 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30543480 0.98 GRB2 (0.46) GRB2NTSR1NTSR2F2OPRD1
SCHEMBL31197912 0.91 GRB2 (0.44) GRB2NTSR1NTSR2OPRD1OPRM1
SCHEMBL30543476 0.91 GRB2 (0.44) GRB2NTSR1NTSR2F2OPRD1
SCHEMBL38651991 0.91 APLNR (0.43) GRB2NTSR1NTSR2F2OPRD1
SCHEMBL38651853 0.91 GRB2 (0.48) GRB2NTSR1NTSR2F2SORT1
SCHEMBL30423238 0.91 GRB2 (0.46) GRB2OPRD1OPRM1BDKRB2CXCR4
SCHEMBL29468766 0.91 GRB2 (0.42) GRB2OPRD1OPRM1BDKRB2
SCHEMBL30414346 0.90 GRB2 (0.42) GRB2OPRD1OPRM1BDKRB2
SCHEMBL31337813 0.89 GRB2 (0.44) GRB2NTSR1OPRD1OPRM1BDKRB2
SCHEMBL29468784 0.89 REN (0.46) GRB2NTSR1NTSR2F2OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2024-12-26 — — US disclosed
EP-4204440-A1 GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-07-05 — — EP disclosed
EP-4146248-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-03-15 — — EP disclosed
WO-2022079639-A1 GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2022-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 GRB2 524/4885NTSR1 78/4885NTSR2 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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