Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14076727 | 0.86 | CCR2 (0.41) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL20098837 | 0.84 | CDK5 (0.44) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL465792 | 0.83 | CCR2 (0.42) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL4076010 | 0.83 | CHRNB2 (0.51) | CCR2LCKSCN9ANR3C2CHRNB2 | |
| SCHEMBL30396325 | 0.83 | CCR2 (0.42) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13141093 | 0.83 | CCR2 (0.41) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL24143765 | 0.83 | L3MBTL1 (0.46) | NPC1RAB9ACCR2 | |
| SCHEMBL2827164 | 0.82 | GLS (0.42) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL21198393 | 0.82 | CCR2 (0.42) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL1022260 | 0.82 | GLS (0.42) | GAAMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739658-A1 | SYNTHESIS OF PYRUVATE KINASE ACTIVATORS | Agios Pharmaceuticals, Inc. (US) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025010390-A1 | SYNTHESIS OF PYRUVATE KINASE ACTIVATORS | AGIOS PHARMACEUTICALS, INC. (US) | 2025-01-09 | — | — | WO | disclosed |