SCHEMBL3134528

SCHEMBL3134528

O=P(O)(O)OC(O)[C@H]1OC(Nc2nc(F)nc3nc[nH]c23)[C@@H](O)[C@@H]1O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.33
TNNI3K Q59H18 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2873813 0.75 ADK (0.43) PAX8
SCHEMBL11468514 0.72 PDPK1 (0.36)
SCHEMBL11478249 0.72 PDPK1 (0.36)
SCHEMBL3150893 0.72 PDPK1 (0.36)
SCHEMBL2287366 0.69 HPRT1 (0.32)
SCHEMBL8042880 0.69
SCHEMBL16008962 0.68 RAB9A (0.38)
SCHEMBL16098965 0.68 RAB9A (0.38)
SCHEMBL9848321 0.68 MEN1 (0.30)
SCHEMBL8596887 0.67 CA12 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046917-A2 FLUDARABINE PHOSPHATE COMPOSITION INTAS PHARMACEUTICALS LIMITED (IN) 2010-04-29 WO disclosed