SCHEMBL31346003

SCHEMBL31346003

N#Cc1cccc(C2Cc3cc(C(F)(F)F)cc(Cl)c3O2)n1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSS P25774 7/20 0.42
ALDH1A1 P00352 1/20 0.31
CTSK P43235 4/20 0.31
MRGPRX4 Q96LA9 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346087 0.85 EZH2 (0.36) CTSSCTSK
SCHEMBL31346145 0.83 TEAD1 (0.33)
SCHEMBL31346083 0.83 TEAD1 (0.33)
SCHEMBL31346014 0.81 CTSS (0.47) CTSSALDH1A1CTSKGAA
SCHEMBL31346162 0.78 CYP19A1 (0.45) MRGPRX4
SCHEMBL31346110 0.78 CYP19A1 (0.45) MRGPRX4
SCHEMBL31345969 0.76 CBFB (0.32)
SCHEMBL31346124 0.76 CTSK (0.35) CTSSCTSK
SCHEMBL31346115 0.74 CTSS (0.36) CTSSCTSK
SCHEMBL31345985 0.71 TEAD1 (0.37) MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712967-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST Enveda Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024239000-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST ENVEDA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed