SCHEMBL31346124

SCHEMBL31346124

N#Cc1cccc(C2Cc3cc(Cl)c(Cl)cc3O2)n1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.35
CTSS P25774 3/20 0.33
LDHA P00338 2/20 0.32
PSMB8 P28062 1/20 0.31
PSMB5 P28074 1/20 0.31
USP30 Q70CQ3 2/20 0.31
DRD4 P21917 2/20 0.31
TTR P02766 1/20 0.30
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
KMO O15229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346115 0.90 CTSS (0.36) CTSKCTSSLDHAUSP30DRD4
SCHEMBL31345970 0.80 TTR (0.32) TTRESR1ESR2
SCHEMBL31346087 0.80 EZH2 (0.36) CTSKCTSSLDHAUSP30DRD4
SCHEMBL31346014 0.78 CTSS (0.47) CTSKCTSS
SCHEMBL31346003 0.76 CTSS (0.42) CTSKCTSS
SCHEMBL31346020 0.74 LDHA (0.49) LDHATTRDRD2
SCHEMBL31346168 0.72
SCHEMBL28931690 0.71 CTSK (0.46) CTSKCTSSUSP30DRD4HTR1A
SCHEMBL31346074 0.71 DPP4 (0.30) TTR
SCHEMBL22463539 0.71 CTSK (0.45) CTSKCTSSUSP30DRD4HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712967-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST Enveda Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024239000-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST ENVEDA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed