SCHEMBL31346121

SCHEMBL31346121

NS(=O)(=O)c1cccc(C2Cc3cc(C(F)(F)F)ccc3O2)c1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.41
CA1 P00915 4/20 0.41
CA9 Q16790 3/20 0.41
CA12 O43570 2/20 0.41
STS P08842 1/20 0.38
FFAR1 O14842 3/20 0.37
AADAT Q8N5Z0 1/20 0.37
KIF11 P52732 1/20 0.37
PKM P14618 1/20 0.36
PKLR P30613 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
CA7 P43166 1/20 0.35
PTGS2 P35354 3/20 0.35
HTR1A P08908 1/20 0.35
CYP19A1 P11511 1/20 0.35
PTGS1 P23219 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346140 0.88 PKM (0.36) CA2CA1STSFFAR1PKM
SCHEMBL31345967 0.81 CA2 (0.37) CA2CA1CA9CA12KIF11
SCHEMBL31346002 0.79 TEAD1 (0.42) FFAR1HTR1ACYP19A1
SCHEMBL31345963 0.79 TEAD1 (0.42) FFAR1HTR1ACYP19A1
SCHEMBL31345959 0.79 PARP1 (0.51) FFAR1CYP19A1
SCHEMBL31346099 0.78 CFTR (0.49) FFAR1PTGS2PTGS1
SCHEMBL31345978 0.78 CFTR (0.49) FFAR1PTGS2PTGS1
SCHEMBL31345995 0.76 CYP19A1 (0.45) FFAR1KIF11HTR1ACYP19A1
SCHEMBL31346117 0.76 CYP19A1 (0.45) FFAR1KIF11HTR1ACYP19A1
SCHEMBL28176992 0.73 HTR1A (0.48) FFAR1HTR1ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712967-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST Enveda Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024239000-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST ENVEDA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed