Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031264 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3CA2KDM4E | |
| SCHEMBL10339219 | 0.91 | CA2 (0.54) | CA2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL1561556 | 0.84 | CYP4F2 (0.49) | CA2KDM4EALDH1A1NOS3NOS1 | |
| SCHEMBL7770968 | 0.83 | ENPP2 (0.52) | CA2KDM4EALDH1A1ENPP2NOS3 | |
| SCHEMBL21728869 | 0.83 | AKR1B1 (0.58) | CA2KDM4ETSHRLMNAPOLB | |
| SCHEMBL29351393 | 0.82 | CA2 (0.45) | CA2KDM4EALDH1A1NOS3NOS1 | |
| SCHEMBL22265815 | 0.82 | CA2 (0.45) | CA2KDM4EALDH1A1NOS3NOS1 | |
| SCHEMBL7770956 | 0.82 | LMNA (0.46) | CA2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL27315443 | 0.82 | KDM4E (0.46) | CA2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL1401775 | 0.81 | AKR1B1 (0.60) | CA2KDM4EALDH1A1ENPP2ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719396-A2 | NON-PEPTIDE SMALL MOLECULE FGF14:NAV1.6 CHANNEL COMPLEX PROTEIN-PROTEIN INTERACTION MODULATORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024254218-A2 | NON-PEPTIDE SMALL MOLECULE FGF14:NAV1.6 CHANNEL COMPLEX PROTEIN-PROTEIN INTERACTION MODULATORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-12-12 | — | — | WO | disclosed |