Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | CALCA | P06881 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347379 | 0.85 | KMT2A (0.54) | ALDH1A1HPGDADORA2AADORA2BMAOB | |
| SCHEMBL14173548 | 0.85 | HPGD (0.52) | LMNAALDH1A1HPGDADORA2ACALCA | |
| SCHEMBL31347370 | 0.85 | MLYCD (0.57) | LMNAHPGD | |
| SCHEMBL5114509 | 0.85 | EGLN1 (0.58) | ALDH1A1THRBPOLBEGLN1 | |
| SCHEMBL31347378 | 0.83 | MMP13 (0.58) | LMNAALDH1A1HPGDMAOBTP53 | |
| SCHEMBL5128898 | 0.82 | CALCA (0.50) | LMNAALDH1A1HPGDADORA2ACALCA | |
| SCHEMBL31347374 | 0.79 | TSHR (0.56) | LMNAALDH1A1TP53POLB | |
| SCHEMBL5253833 | 0.79 | RAB9A (0.55) | LMNAALDH1A1HPGDADORA2ACALCA | |
| SCHEMBL5119038 | 0.78 | ADORA2A (0.53) | LMNAALDH1A1HPGDADORA2ACALCA | |
| SCHEMBL31347385 | 0.78 | EGLN1 (0.61) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371360-A | 5, 6-Dihydroxypyrimidine compound and preparation method and application thereof | 暨南大学 | 2025-01-28 | — | — | CN | disclosed |