Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16649161 | 0.75 | CYP11B1 (0.46) | SMN1; SMN2GAATDP1CYP11B1CYP11B2 | |
| SCHEMBL30055347 | 0.74 | ALDH1A1 (0.49) | SMN1; SMN2GAATDP1CYP11B1CYP11B2 | |
| SCHEMBL31350596 | 0.74 | OPRK1 (0.36) | SMN1; SMN2GAATDP1CYP11B1CYP11B2 | |
| SCHEMBL4766176 | 0.74 | CYP11B1 (0.42) | SMN1; SMN2GAACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL2634852 | 0.74 | ALDH1A1 (0.49) | SMN1; SMN2GAATDP1CYP11B1CYP11B2 | |
| SCHEMBL16139574 | 0.74 | CYP11B1 (0.42) | SMN1; SMN2GAACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL31350683 | 0.74 | OPRK1 (0.36) | SMN1; SMN2GAATDP1CYP11B1CYP11B2 | |
| SCHEMBL582977 | 0.74 | ALDH1A1 (0.46) | SMN1; SMN2GAACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL31350832 | 0.74 | CHEK1 (0.37) | SMN1; SMN2TDP1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL24147640 | 0.70 | AGBL2 (0.40) | SMN1; SMN2GAATDP1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743462-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012643-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2025-01-16 | — | — | WO | disclosed |