Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | GAA | P10253 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13723749 | 0.85 | NR4A1 (0.49) | NR4A1ALDH1A1ALDH1A3DRD2MAPT | |
| SCHEMBL15358685 | 0.84 | NR4A1 (0.61) | NR4A1ALDH1A1ALDH1A3DRD2MAPT | |
| SCHEMBL10036161 | 0.84 | NR4A1 (0.50) | NR4A1ALDH1A1ALDH1A3DRD2MAPT | |
| SCHEMBL23126654 | 0.81 | DRD2 (0.48) | NR4A1ALDH1A1ALDH1A3DRD2MAPT | |
| SCHEMBL1930522 | 0.81 | ALDH1A1 (0.59) | NR4A1ALDH1A1ALDH1A3MAPTGAA | |
| SCHEMBL16305337 | 0.80 | LGMN (0.47) | NR4A1ALDH1A1ALDH1A3DRD2MAPT | |
| SCHEMBL15244255 | 0.80 | NR4A1 (0.47) | NR4A1ALDH1A1ALDH1A3DRD2MAPT | |
| SCHEMBL14320542 | 0.80 | NR4A1 (0.47) | NR4A1ALDH1A1ALDH1A3DRD2MAPT | |
| SCHEMBL15650361 | 0.80 | NR4A1 (0.47) | NR4A1ALDH1A1ALDH1A3DRD2MAPT | |
| SCHEMBL17076804 | 0.80 | NR4A1 (0.47) | NR4A1ALDH1A1ALDH1A3DRD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586713-A | Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases | 百济神州(苏州)生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |