Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31353534 | 0.80 | GRM2 (0.34) | GRM2LDHALDHBPOLB | |
| SCHEMBL31353406 | 0.80 | GRM2 (0.40) | GRM2LDHALDHBGPR35PTGS1 | |
| SCHEMBL31353619 | 0.76 | GRM2 (0.41) | RAB9ANPC1MEN1KMT2AALOX15 | |
| SCHEMBL24897763 | 0.74 | CA3 (0.40) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL21938179 | 0.73 | ACHE (0.46) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL21363124 | 0.73 | SELL (0.48) | RAB9ANPC1MEN1KMT2AALOX15 | |
| SCHEMBL12148763 | 0.71 | ACHE (0.43) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL31353168 | 0.71 | LMNA (0.35) | RAB9AKMT2AALOX15GRM2KDM4E | |
| SCHEMBL21363228 | 0.69 | ALOX15 (0.48) | RAB9ANPC1MEN1KMT2AALOX15 | |
| SCHEMBL19067821 | 0.69 | ALOX15 (0.54) | RAB9ANPC1MEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586713-A | Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases | 百济神州(苏州)生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |