Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
| ▸ | SELE | P16581 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22888513 | 0.77 | TRPA1 (0.41) | ALOX15RPS6KA3GSK3BPTGS2PTGS1 | |
| SCHEMBL8855072 | 0.77 | GABRA1 (0.47) | RPS6KA3GSK3BPTGS2PTGS1CA3 | |
| SCHEMBL8120400 | 0.76 | SELL (0.72) | SELLSELPSELENPC1KMT2A | |
| SCHEMBL28146420 | 0.75 | F2 (0.49) | SELLSELPSELEALDH1A1 | |
| SCHEMBL29406938 | 0.74 | ACHE (0.44) | NPC1RAB9AKMT2AMEN1PTGS2 | |
| SCHEMBL30286418 | 0.73 | RPS6KA3 (0.46) | KMT2AMEN1ALOX15RPS6KA3PTGS2 | |
| SCHEMBL28692859 | 0.73 | ACLY (0.55) | SELLSELPSELEKMT2AMEN1 | |
| SCHEMBL31353263 | 0.73 | RAB9A (0.40) | NPC1RAB9AKMT2AMEN1ALOX15 | |
| SCHEMBL20508878 | 0.73 | MGAM (0.48) | ACHEALDH1A1GAABACE1 | |
| SCHEMBL21363228 | 0.72 | ALOX15 (0.48) | NPC1RAB9AKMT2AMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178119-A1 | AMINOCOUMARIN COMPOUNDS AND METHODS OF THEIR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-09-19 | — | — | WO | disclosed |