SCHEMBL31359443

SCHEMBL31359443

CS(=O)(=O)O[C@@]1(O)[C@@H](COP(=O)(O)OP(=O)(O)O)O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 1/20 0.56
▸ FUT5 Q11128 1/20 0.54
▸ NT5E P21589 1/20 0.53
▸ POLB P06746 1/20 0.53
▸ KRAS P01116 3/20 0.51
▸ P2RY6 Q15077 2/20 0.50
▸ P2RY2 P41231 1/20 0.50
▸ P2RY4 P51582 1/20 0.50
▸ PNP P00491 1/20 0.49
▸ POLG P54098 1/20 0.48
▸ DCPS Q96C86 1/20 0.48
▸ ENPP1 P22413 2/20 0.46
▸ P2RY1 P47900 2/20 0.46
▸ P2RY12 Q9H244 1/20 0.46
▸ TAS1R3 Q7RTX0 1/20 0.46
▸ TAS1R1 Q7RTX1 1/20 0.46
▸ HINT1 P49773 3/20 0.46
▸ P2RX1 P51575 1/20 0.46
▸ P2RX3 P56373 1/20 0.46
▸ P2RY11 Q96G91 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29093384 0.91 TGM2 (0.58) TGM2FUT5NT5EPOLBKRAS
SCHEMBL30579774 0.84 TGM2 (0.39) TGM2FUT5NT5EPOLBKRAS
SCHEMBL29093004 0.84 NT5E (0.56) TGM2FUT5NT5EPOLBKRAS
Deoxy Adenosinediphosphate SCHEMBL5827749 0.81 TGM2 (0.63) TGM2FUT5NT5EPOLBKRAS
Deoxy Adenosinediphosphate SCHEMBL5827743 0.81 TGM2 (0.63) TGM2FUT5NT5EPOLBKRAS
SCHEMBL31574037 0.80 KRAS (0.56) TGM2FUT5NT5EPOLBKRAS
SCHEMBL22110041 0.80 TGM2 (0.72) TGM2FUT5NT5EPOLBKRAS
SCHEMBL1913809 0.80 TGM2 (0.62) TGM2FUT5NT5EPOLBKRAS
SCHEMBL17371166 0.80 TGM2 (0.72) TGM2FUT5NT5EPOLBKRAS
SCHEMBL25712474 0.80 TGM2 (0.62) TGM2FUT5NT5EPOLBKRAS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12522630-B2 MRNA cap analog and uses thereof HANMI FINE CHEMICAL CO., LTD. (KR) 2026-01-13 — — US disclosed
US-20250230183-A1 MRNA CAP ANALOG AND USES THEREOF HANMI FINE CHEMICAL CO., LTD. (KR) 2025-07-17 — — US disclosed
WO-2025071359-A1 MRNA CAP ANALOG AND USE THEREOF 한미정밀화학 주식회사 2025-04-03 — — WO disclosed
EP-4506353-A1 MRNA CAP ANALOG AND USES THEREOF Hanmi Fine Chemical Co., Ltd. (KR) 2025-02-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230183-A1 MRNA CAP ANALOG AND USES THEREOF RNGTT, RNMT, CAP1 TGM2 4453/4885FUT5 1822/4885NT5E 1310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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