Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 14/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 14/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16563233 | 0.98 | KIF11 (0.45) | KIF11TSHRBCHEACHELMNA | |
| SCHEMBL29738899 | 0.90 | SLC22A2 (0.43) | KIF11TSHRBCHEACHELMNA | |
| Hydrochloric Acid SCHEMBL2261291 | 0.79 | ANPEP (0.39) | KIF11 | |
| Hydrochloric Acid SCHEMBL601282 | 0.79 | ACHE (0.40) | BCHEACHE | |
| SCHEMBL19601089 | 0.79 | TSHR (0.35) | KIF11TSHRBCHEACHELMNA | |
| Hydrochloric Acid SCHEMBL16563223 | 0.76 | KIF11 (0.49) | KIF11BCHEACHELMNA | |
| SCHEMBL19892477 | 0.76 | KIF11 (0.48) | KIF11TSHRBCHEACHE | |
| SCHEMBL22845688 | 0.76 | BCHE (0.47) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL2469434 | 0.75 | RAB9A (0.42) | BCHEACHE | |
| SCHEMBL16563098 | 0.74 | KIF11 (0.46) | KIF11BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100091353-A1 | DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-04-15 | — | — | US | disclosed |