Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2263262 | 0.85 | MMP8 (0.36) | — | |
| Hydrochloric Acid SCHEMBL2264607 | 0.83 | MMP2 (0.37) | — | |
| SCHEMBL4330742 | 0.83 | MMP8 (0.37) | PTPN5 | |
| Hydrochloric Acid SCHEMBL1227055 | 0.81 | ACP3 (0.34) | PTPN5 | |
| Hydrochloric Acid SCHEMBL2259936 | 0.80 | MMP2 (0.39) | PTPN5KIF11 | |
| SCHEMBL1226946 | 0.79 | ACP3 (0.35) | PTPN5 | |
| Hydrochloric Acid SCHEMBL3136051 | 0.79 | KIF11 (0.48) | KIF11 | |
| Hydrochloric Acid SCHEMBL601282 | 0.78 | ACHE (0.40) | ANPEPERAP2 | |
| Hydrochloric Acid SCHEMBL6446792 | 0.78 | RAB9A (0.38) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2262115 | 0.78 | MMP2 (0.41) | PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | NTERA LIMITED (IE) | 2009-10-15 | — | — | US | claimed |
| US-20060110638-A1 | Electrochromic compounds | NTERA LIMITED (IE) | 2006-05-25 | — | — | US | claimed |
| EP-1443091-A1 | Electrochromic compounds | Ntera Limited (IE) | 2004-08-04 | — | — | EP | claimed |
| US-8999430-B2 | Method of manufacturing display element | KONICA MINOLTA HOLDINGS, INC. (JP) | 2015-04-07 | — | — | US | disclosed |
| EP-2149816-B1 | METHOD OF MANUFACTURING AN ELECTROCHROMIC DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS INC (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8014056-B2 | Display element and method of driving the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-8004742-B2 | Electrochromic display device | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20100166946-A1 | METHOD OF MANUFACTURING DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-07-01 | — | — | US | disclosed |
| US-20100091353-A1 | DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-04-15 | — | — | US | disclosed |
| EP-2149816-A1 | METHOD FOR PRODUCTION OF DISPLAY ELEMENT | Konica Minolta Holdings, Inc. (JP) | 2010-02-03 | — | — | EP | disclosed |
| US-20090316249-A1 | ELECTROCHROMIC DISPLAY DEVICE | KONICA MINOLTA HOLDINGS, INC. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | NTERA LIMITED (IE) | 2009-10-15 | — | — | US | disclosed |
| EP-2096490-A1 | DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME | Konica Minolta Holdings, Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-7567371-B2 | Electrochromic compounds | NTERA LIMITED (IE) | 2009-07-28 | — | — | US | disclosed |
| EP-2040115-A1 | ELECTROCHROMIC DISPLAY DEVICE | Konica Minolta Holdings, Inc. (JP) | 2009-03-25 | — | — | EP | disclosed |
| US-20060110638-A1 | Electrochromic compounds | NTERA LIMITED (IE) | 2006-05-25 | — | — | US | disclosed |
| EP-1443091-A1 | Electrochromic compounds | Ntera Limited (IE) | 2004-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | ETV6, HCN2, EED | ANPEP 4231/4885ERAP2 1838/4885PTPN5 2907/4885 |
| US-20060110638-A1 | Electrochromic compounds | ETV6, HCN2, EED | ANPEP 4231/4885ERAP2 1838/4885PTPN5 2907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.