Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.32 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | MET | P08581 | 4/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31360827 | 0.82 | CHRNB2 (0.34) | P2RX7METPDE3BPDE3APDE10A | |
| SCHEMBL26988872 | 0.80 | P2RX7 (0.33) | MAPTCYP2D6GSK3BCYP1A2P2RX7 | |
| SCHEMBL30722815 | 0.80 | P2RX7 (0.33) | MAPTCYP2D6GSK3BCYP1A2P2RX7 | |
| SCHEMBL30722734 | 0.78 | SIRT6 (0.37) | MAPTP2RX7KCNH2 | |
| SCHEMBL26988396 | 0.78 | SIRT6 (0.37) | MAPTP2RX7KCNH2 | |
| SCHEMBL359423 | 0.74 | POLB (0.56) | POLBMAPTCYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL31360856 | 0.71 | P2RX7 (0.34) | CYP2D6GSK3BCYP1A2CSNK1A1GSK3A | |
| SCHEMBL31425103 | 0.69 | EIF2AK4 (0.38) | CYP2D6GSK3BCYP1A2P2RX7PDE10A | |
| SCHEMBL16684517 | 0.69 | POLB (0.49) | POLBMAPTCYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL26340591 | 0.67 | DRD3 (0.36) | CYP2D6GSK3BP2RX7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747249-A1 | TREM2 MODULATORS | Muna Therapeutics ApS (DK) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017059-A1 | TREM2 MODULATORS | MUNA THERAPEUTICS APS (DK) | 2025-01-23 | — | — | WO | disclosed |