Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30722815 | 1.00 | P2RX7 (0.33) | P2RX7KCNH2MAPTSPRCYP1A2 | |
| SCHEMBL26988396 | 0.90 | SIRT6 (0.37) | P2RX7KCNH2MAPTSPR | |
| SCHEMBL30722734 | 0.90 | SIRT6 (0.37) | P2RX7KCNH2MAPTSPR | |
| SCHEMBL31360909 | 0.80 | POLB (0.34) | P2RX7KCNH2MAPTCYP1A2CYP2D6 | |
| SCHEMBL26988922 | 0.73 | P2RX7 (0.35) | P2RX7CYP1A2CYP2D6GSK3B | |
| SCHEMBL31411026 | 0.73 | P2RX7 (0.35) | P2RX7CYP1A2CYP2D6GSK3B | |
| SCHEMBL31360827 | 0.72 | CHRNB2 (0.34) | P2RX7 | |
| SCHEMBL26988926 | 0.70 | PDE2A (0.37) | P2RX7SPRCYP1A2CYP2D6GSK3B | |
| SCHEMBL31360856 | 0.70 | P2RX7 (0.34) | P2RX7CYP1A2CYP2D6GSK3B | |
| SCHEMBL34470579 | 0.67 | GSK3B (0.38) | P2RX7KCNH2CYP1A2CYP2D6GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551575-A2 | TREM2 MODULATORS | Muna Therapeutics ApS (DK) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024008722-A2 | TREM2 MODULATORS | MUNA THERAPEUTICS APS (DK) | 2024-01-11 | — | — | WO | disclosed |