Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.43 |
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758401 | 0.74 | ALDH1A1 (0.59) | HPGDALDH1A1MAPK1NPSR1RXFP1 | |
| SCHEMBL7755160 | 0.72 | ADORA2B (0.44) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL4472274 | 0.71 | ADORA1 (0.45) | ADORA1ADORA2APDE4APDE4BPDE4C | |
| SCHEMBL7270107 | 0.71 | ADORA1 (0.59) | ADORA1ADORA2APDE4APDE4BPDE4C | |
| SCHEMBL14267088 | 0.70 | ADORA2A (0.43) | ADORA1ADORA2APDE4APDE4BPDE4C | |
| SCHEMBL7758347 | 0.70 | ADORA3 (0.48) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7758386 | 0.70 | ADORA3 (0.48) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7761664 | 0.69 | ADORA3 (0.46) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL31060755 | 0.69 | ADORA1 (0.89) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7759707 | 0.69 | ADORA3 (0.46) | ADORA1ADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075935-A1 | XANTHINE MODULATORS OF ADENOSINE A1 RECEPTOR | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075935-A1 | XANTHINE MODULATORS OF ADENOSINE A1 RECEPTOR | ADORA1, ADORA2A, ADORA3 | ADORA1 1/4885ADORA2A 2/4885PDE4A 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.