SCHEMBL31362974

SCHEMBL31362974

COC(=O)N(Cc1ccc(C)cc1C)NC(=O)c1c(Oc2cccc(Cl)c2)nnn1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
MGLL Q99685 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
P2RX4 Q99571 3/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 3/20 0.32
PPARA Q07869 3/20 0.32
PPARD Q03181 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
NPC1 O15118 1/20 0.32
F2 P00734 1/20 0.32
RAB9A P51151 1/20 0.32
HIF1A Q16665 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31363079 0.89 P2RY1 (0.38) CYP1A2CYP2C9CYP2C19SMN1; SMN2LMNA
SCHEMBL31362970 0.80 AKR1C3 (0.40) CYP1A2CYP2C9CYP2C19SMN1; SMN2MEN1
SCHEMBL31362977 0.76 LMNA (0.40) CYP1A2CYP2C9CYP2C19SMN1; SMN2LMNA
SCHEMBL31363064 0.73 CYP1A2 (0.43) CYP1A2CYP2C9CYP2C19MGLLSMN1; SMN2
SCHEMBL31362930 0.72 CYP1A2 (0.41) CYP1A2CYP2C9CYP2C19MGLLSMN1; SMN2
SCHEMBL31362978 0.72 ALDH1A1 (0.32) CYP1A2LMNAMEN1KMT2APPARG
SCHEMBL31362973 0.70 MAPT (0.35) CYP1A2CYP2C9CYP2C19SMN1; SMN2LMNA
SCHEMBL31363012 0.70 LMNA (0.34) SMN1; SMN2LMNAMEN1KMT2ANPC1
SCHEMBL31163277 0.69 LMNA (0.37) CYP2C9CYP2C19SMN1; SMN2LMNAMEN1
SCHEMBL30919473 0.67 NR3C1 (0.35) CYP1A2CYP2C9CYP2C19SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025033011-A1 FIVE-MEMBERED HETEROARYL COMPOUND AND AGRICULTURAL AND HORTICULTURAL BACTERICIDE 日本曹達株式会社 2025-02-13 WO disclosed