Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 3/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 2/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30067156 | 0.85 | KEAP1 (0.46) | CASP1LMNAALDH1A1KEAP1NFE2L2 | |
| SCHEMBL31368745 | 0.84 | DGAT1 (0.41) | CASP1LMNADGAT1POLBKEAP1 | |
| SCHEMBL21195978 | 0.81 | LMNA (0.41) | CASP1LMNAALDH1A1POLBIKBKB | |
| SCHEMBL31364654 | 0.81 | LMNA (0.41) | CASP1LMNAALDH1A1POLBIKBKB | |
| SCHEMBL26040458 | 0.80 | NQO2 (0.46) | CASP1ALDH1A1POLB | |
| SCHEMBL21216359 | 0.78 | POLB (0.58) | LMNAALDH1A1POLBIKBKBCHUK | |
| SCHEMBL21196095 | 0.75 | CASP1 (0.42) | CASP1LMNAALDH1A1POLBIKBKB | |
| SCHEMBL31558179 | 0.75 | CASP1 (0.42) | CASP1LMNAALDH1A1POLBIKBKB | |
| SCHEMBL27240208 | 0.74 | POLB (0.44) | LMNAALDH1A1POLBNNMT | |
| SCHEMBL4663299 | 0.73 | ALDH1A1 (0.42) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025020886-A1 | AZAQUINAZOLINE RING DERIVATIVE AND USE THEREOF | 浙江星浩澎博医药有限公司 | 2025-01-30 | — | — | WO | disclosed |