Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | NCEH1 | Q6PIU2 | 10/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488962 | 0.88 | HTT (0.54) | HTTNCEH1GAAKDM4EMAPT | |
| SCHEMBL27498190 | 0.83 | ALDH1A1 (0.50) | HTTNCEH1GAAKDM4EMAPT | |
| SCHEMBL27489224 | 0.82 | NCEH1 (0.49) | HTTNCEH1GAAMAPTALDH1A1 | |
| SCHEMBL4225247 | 0.81 | NCEH1 (0.48) | HTTNCEH1GAAKDM4EHSD17B10 | |
| SCHEMBL12199931 | 0.80 | MAPT (0.58) | HTTNCEH1GAAKDM4EMAPT | |
| SCHEMBL10334136 | 0.80 | NCEH1 (0.71) | HTTNCEH1GAAKDM4EMAPT | |
| SCHEMBL30710587 | 0.80 | MAPT (0.58) | HTTNCEH1GAAKDM4EMAPT | |
| SCHEMBL455028 | 0.79 | MAPT (0.53) | HTTNCEH1KDM4EMAPTALDH1A1 | |
| SCHEMBL29357471 | 0.79 | MAPT (0.53) | HTTNCEH1KDM4EMAPTALDH1A1 | |
| SCHEMBL11894598 | 0.78 | LMNA (0.54) | HTTNCEH1GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021195-A1 | STEROID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 珂阑(上海)医药科技有限公司 | 2025-01-30 | — | — | WO | disclosed |
| WO-2025020190-A1 | STEROID COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | 珂阑(上海)医药科技有限公司 | 2025-01-30 | — | — | WO | disclosed |