Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2340667 | 0.85 | CYP1A2 (0.58) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2340670 | 0.85 | CYP1A2 (0.58) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28083812 | 0.81 | TRPA1 (0.52) | CYP1A2CYP2D6PPARARAB9ANPC1 | |
| Carbamic Acid Phenyl Ester SCHEMBL667176 | 0.81 | PPARA (0.46) | PLAUPPARARAB9ANPC1PRSS1 | |
| SCHEMBL31366711 | 0.77 | CYP2C9 (0.58) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31366700 | 0.77 | L3MBTL1 (0.48) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14524521 | 0.77 | RAB9A (0.49) | PLAUPPARARAB9ANPC1PRSS1 | |
| SCHEMBL1694498 | 0.76 | NPC1 (0.56) | CYP1A2CYP2C9CYP2C19PPARARAB9A | |
| SCHEMBL1694500 | 0.76 | NPC1 (0.56) | CYP1A2CYP2C9CYP2C19PPARARAB9A | |
| SCHEMBL1728537 | 0.73 | MAPK14 (0.68) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945572-B | HBF pharmacological inducing compounds for the treatment of sickle cell anemia and beta-thalassemia | 周美吟 | 2025-01-28 | — | — | CN | disclosed |