Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 3/20 | 0.44 |
| ▸ | KLK8 | O60259 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | KLK2 | P20151 | 2/20 | 0.42 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114506 | 0.91 | PLAU (0.50) | PPARAPPARGPPARDPLAUMEN1 | |
| SCHEMBL114505 | 0.91 | PLAU (0.50) | PPARAPPARGPPARDPLAUMEN1 | |
| SCHEMBL28083812 | 0.83 | TRPA1 (0.52) | PPARAPPARGPPARDF2PRSS1 | |
| SCHEMBL29017558 | 0.81 | MAPT (0.48) | PPARAPPARGPPARDPLAUMEN1 | |
| Carbamic Acid Phenyl Ester SCHEMBL31366706 | 0.81 | TSHR (0.48) | PPARAPLAUPRSS1ACRTMPRSS15 | |
| SCHEMBL11469482 | 0.79 | PPARG (0.49) | PPARAPPARGPPARDPLAUMEN1 | |
| SCHEMBL11469483 | 0.79 | PPARG (0.49) | PPARAPPARGPPARDPLAUMEN1 | |
| SCHEMBL158284 | 0.78 | ALDH1A1 (0.49) | PPARAPPARDKMT2ANPC1ALDH1A1 | |
| SCHEMBL1539603 | 0.78 | ALDH1A1 (0.49) | PPARAPPARDKMT2ANPC1ALDH1A1 | |
| SCHEMBL994449 | 0.76 | LMNA (0.58) | PPARAPPARGPPARDTRPA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376133-A9 | CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-11-14 | — | — | US | disclosed |
| US-20230416283-A1 | CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-12-28 | — | — | US | disclosed |
| EP-3172213-B1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2021-09-22 | — | — | EP | disclosed |
| EP-2920197-B1 | PROLINE-LOCKED STAPLED PEPTIDES AND USES THEREOF | HARVARD COLLEGE (US) | 2021-03-17 | — | — | EP | disclosed |
| US-20120046282-A1 | METHODS AND COMPOUNDS FOR ANTIMICROBIAL INTERVENTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376133-A9 | CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS | PGD, CDCA2, MCM2 | PPARA 4745/4885PPARG 4466/4885PPARD 4762/4885 |
| US-20120046282-A1 | METHODS AND COMPOUNDS FOR ANTIMICROBIAL INTERVENTION | FDFT1, COASY, KAT5 | PPARA 3639/4885PPARG 3534/4885PPARD 4211/4885 |
| US-20230416283-A1 | CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS | PGD, CDCA2, MCM2 | PPARA 4745/4885PPARG 4466/4885PPARD 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.