Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.35 |
| ▸ | TNKS | O95271 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31367983 | 0.89 | SCD (0.37) | SCDPTPN11MEN1KMT2APDE3B | |
| SCHEMBL31368005 | 0.79 | POLB (0.36) | POLBTNKS2TNKSPARP1SCD | |
| SCHEMBL31367986 | 0.79 | POLB (0.43) | POLBTNKS2TNKSPARP1TLR9 | |
| SCHEMBL31367998 | 0.77 | POLB (0.39) | POLBTNKS2TNKSPARP1TLR9 | |
| SCHEMBL31368003 | 0.75 | HCAR1 (0.40) | TNKS2TNKSPARP1SCDPTPN11 | |
| SCHEMBL31367978 | 0.72 | PDE3B (0.38) | SCDMEN1TSHRKMT2APDE3B | |
| SCHEMBL29294905 | 0.70 | PDE3B (0.39) | SCDKMT2AFLT3PDE3BPDE3A | |
| SCHEMBL31367991 | 0.68 | ADORA3 (0.36) | TNKS2TNKSMEN1MAPK1KMT2A | |
| SCHEMBL31368033 | 0.67 | PDE2A (0.35) | TNKS2TNKSPARP1SCDMEN1 | |
| SCHEMBL31367976 | 0.66 | KMT2A (0.41) | MEN1TSHRMAPK1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092051-A1 | NLRP3 MODULATORS AND USE THEREOF | Bioentropy Inc. (US) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092051-A1 | NLRP3 MODULATORS AND USE THEREOF | NLRP3, NLRP1, NOD1 | POLB 4713/4885TNKS2 1381/4885TNKS 825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.