SCHEMBL31369826

SCHEMBL31369826

N[C@@H](CCc1cccc(O)c1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 2/20 0.59
ANPEP P15144 1/20 0.55
ERAP2 Q6P179 1/20 0.55
ERAP1 Q9NZ08 1/20 0.55
DRD2 P14416 1/20 0.53
DRD1 P21728 1/20 0.53
TAAR1 Q96RJ0 1/20 0.53
KYNU Q16719 1/20 0.53
GRIK1 P39086 1/20 0.52
GRIA1 P42261 1/20 0.52
GRIA3 P42263 1/20 0.52
GRIA4 P48058 1/20 0.52
GRIK2 Q13002 1/20 0.52
GRIK3 Q13003 1/20 0.52
SLC7A5 Q01650 2/20 0.49
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
PTGS1 P23219 1/20 0.49
XIAP P98170 1/20 0.49
KIF11 P52732 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27634017 1.00 GRIA2 (0.59) GRIA2ANPEPERAP2ERAP1DRD2
SCHEMBL6377902 0.83 MAOA (0.55) GRIA2GRIK1GRIA1GRIA3GRIA4
SCHEMBL6378815 0.83 GRIK1 (0.52) GRIA2ANPEPERAP1GRIK1GRIA1
SCHEMBL31370062 0.83 MAOA (0.55) GRIA2GRIK1GRIA1GRIA3GRIA4
SCHEMBL13537526 0.83 GRIA2 (0.82) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL458080 0.83 GRIA2 (0.82) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL29430938 0.83 GRIA2 (0.82) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL4356402 0.83 GRIA2 (0.82) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL22721343 0.83 GRIA2 (0.82) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL31453795 0.83 GRIA2 (0.82) GRIA2SLC7A5ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 GRIA2 1319/4885ANPEP 16/4885ERAP2 388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.