Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | AOC1 | P19801 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14558811 | 0.86 | ROCK2 (0.46) | ROCK2TMEM97SIGMAR1RIPK1SCD5 | |
| SCHEMBL14558766 | 0.85 | TMEM97 (0.48) | TMEM97SIGMAR1ADAM17RIPK1FABP7 | |
| SCHEMBL14558757 | 0.83 | TMEM97 (0.47) | TMEM97SIGMAR1ADAM17RIPK1FABP7 | |
| SCHEMBL5150024 | 0.83 | TMEM97 (0.41) | ROCK2TMEM97SIGMAR1ADAM17RIPK1 | |
| SCHEMBL5150021 | 0.83 | TMEM97 (0.41) | ROCK2TMEM97SIGMAR1ADAM17RIPK1 | |
| SCHEMBL14558770 | 0.82 | TMEM97 (0.42) | TMEM97SIGMAR1ADAM17RIPK1SCD5 | |
| Acetic Acid SCHEMBL27570248 | 0.81 | ROCK2 (0.44) | ROCK2TMEM97SIGMAR1ADAM17ALDH1A1 | |
| SCHEMBL5156573 | 0.81 | HSP90AA1 (0.45) | ROCK2TMEM97SIGMAR1ALDH1A1GAA | |
| SCHEMBL31369417 | 0.79 | FFAR2 (0.44) | FABP7FABP5 | |
| SCHEMBL23157205 | 0.78 | KMT2A (0.43) | ALDH1A1GAAFABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | ROCK2 4254/4885TMEM97 2178/4885SIGMAR1 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.