Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31373271 | 0.98 | CALM1 (0.46) | CALM1TP53LOXL2KCNH2APOBEC3A | |
| SCHEMBL2727907 | 0.77 | ALDH1A1 (0.50) | CALM1TP53KCNH2APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL2006410 | 0.75 | CALM1 (0.44) | CALM1TP53KCNH2APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL11725090 | 0.73 | KDM4E (0.45) | CALM1ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL14740720 | 0.71 | CALM1 (0.44) | CALM1TP53LOXL2KCNH2APOBEC3A | |
| Bromide SCHEMBL28254649 | 0.71 | CALM1 (0.44) | CALM1TP53KCNH2APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL5688232 | 0.71 | CALM1 (0.39) | CALM1TP53KCNH2APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL10533908 | 0.71 | CALM1 (0.39) | CALM1TP53KCNH2APOBEC3AAPOBEC3G | |
| Bromide SCHEMBL10904035 | 0.70 | TP53 (0.39) | TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL6423133 | 0.69 | CA2 (0.39) | CALM1KCNH2ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119185090-A | High-moisturizing-performance cream, preparation method thereof and cream tissue | 珠海金鸡化工有限公司 | 2024-12-27 | — | — | CN | disclosed |