Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | MRE11 | P49959 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13040760 | 0.84 | IDO1 (0.49) | CNR1PTGES2KDRCTSSCTSK | |
| SCHEMBL16675760 | 0.83 | CNR1 (0.48) | CNR1PTGES2KDRBTK | |
| SCHEMBL13271123 | 0.77 | CNR1 (0.41) | CNR1PTGES2KDRCTSSCTSK | |
| SCHEMBL3137904 | 0.76 | CTSS (0.39) | CTSSCTSKPPARGPPARAALDH1A1 | |
| SCHEMBL12499023 | 0.76 | CNR1 (0.49) | CNR1PTGES2KDRBTKMETAP2 | |
| SCHEMBL3141702 | 0.75 | CTSS (0.39) | CTSSCTSKPPARGPPARAALDH1A1 | |
| SCHEMBL20710589 | 0.75 | CNR1 (0.46) | CNR1PTGES2KDRCTSSCTSK | |
| SCHEMBL1360819 | 0.75 | RAB9A (0.60) | CNR1PTGES2KDRBTKNPC1 | |
| SCHEMBL30469304 | 0.74 | NPC1 (0.49) | CNR1PTGES2KDRBTKMETAP2 | |
| SCHEMBL2627239 | 0.74 | NPC1 (0.49) | CNR1PTGES2KDRBTKMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825249-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2010-11-02 | — | — | US | disclosed |
| EP-1749014-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-07-07 | — | — | EP | disclosed |
| US-20070249834-A1 | Metal Complexes | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2007-10-25 | — | — | US | disclosed |
| EP-1749014-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005113563-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249834-A1 | Metal Complexes | SOD1, AP1M1, AP2A1 | CNR1 3626/4885PTGES2 1339/4885KDR 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.