Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141702 | 0.98 | CTSS (0.39) | CTSSCTSKGRIA2ALDH1A1POLB | |
| SCHEMBL13040762 | 0.81 | IDO1 (0.51) | CTSSCTSKALDH1A1POLBMAPT | |
| SCHEMBL3137478 | 0.76 | CNR1 (0.47) | CTSSCTSKALDH1A1RAB9APPARG | |
| SCHEMBL13271106 | 0.74 | CTSS (0.39) | CTSSCTSKKARS1PRMT6IDO1 | |
| SCHEMBL1028576 | 0.72 | MEN1 (0.68) | ALDH1A1POLBMAPTHPGDHSD17B10 | |
| SCHEMBL7905978 | 0.72 | ALDH1A1 (0.53) | ALDH1A1POLBMAPTHPGDMEN1 | |
| SCHEMBL1074467 | 0.69 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTHPGDHSD17B10 | |
| SCHEMBL3623102 | 0.67 | IDO1 (0.59) | CTSSCTSKALDH1A1POLBMAPT | |
| SCHEMBL14732765 | 0.67 | CTSS (0.54) | CTSSCTSKPPARGPPARAKARS1 | |
| SCHEMBL29992115 | 0.66 | ALDH1A1 (0.44) | ALDH1A1POLBMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825249-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2010-11-02 | — | — | US | disclosed |
| EP-1749014-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-07-07 | — | — | EP | disclosed |
| US-20070249834-A1 | Metal Complexes | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2007-10-25 | — | — | US | disclosed |
| EP-1749014-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005113563-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249834-A1 | Metal Complexes | SOD1, AP1M1, AP2A1 | CTSS 2313/4885CTSK 3301/4885GRIA2 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.