SCHEMBL29558140

SCHEMBL29558140

c1ccc2c(c1)COC21c2ccccc2Oc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
AVPR1A P37288 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALOX5 P09917 1/20 0.34
SLC6A4 P31645 2/20 0.34
CHRM3 P20309 1/20 0.33
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24401890 0.86 FTO (0.51) RAB9A
SCHEMBL24401901 0.86 FTO (0.51) RAB9A
SCHEMBL11687105 0.82 LMNA (0.45) MAOAMAOBGAANPC1LMNA
SCHEMBL16602965 0.82 PARP1 (0.36) MAOAMAOBAVPR1ALMNACHRM3
SCHEMBL31376332 0.82 LMNA (0.45) MAOAMAOBGAANPC1LMNA
SCHEMBL3794922 0.82 FTO (0.54) LMNARAB9A
SCHEMBL28492898 0.82 HTR2A (0.44) MAOAMAOBSLC6A4SIGMAR1
SCHEMBL11711333 0.80 LMNA (0.43) MAOAMAOBGAANPC1LMNA
SCHEMBL841189 0.80 ALDH1A1 (0.37) LMNASLC6A4
SCHEMBL31018346 0.80 ALOX5 (0.48) GAAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102257-A2 COMPOSITIONS AND METHODS FOR NUCLEIC ACID AMPLIFICATION TRACERDX, INC. (US) 2026-05-15 WO disclosed
WO-2025104141-A1 NOVEL REVERSIBLE FLUORESCENT PROBES FOR CB2 F. HOFFMANN-LA ROCHE AG (CH) 2025-05-22 WO disclosed
US-20250024837-A1 PESTICIDE SYSTEM BANISH, MICHELE 2025-01-23 US disclosed
US-20240299591-A1 Antimicrobial Peptides and Their Use THE UNIVERSITY OF MANCHESTER (GB) 2024-09-12 US disclosed
EP-4392493-A1 AZETIDINE SUBSTITUTED ROSAMINES USEFUL FOR STAINING MITOCHONDRIA Tocris Cookson Limited (GB) 2024-07-03 EP disclosed
EP-4362988-A1 ANTIMICROBIAL PEPTIDES AND THEIR USE The University of Manchester (GB) 2024-05-08 EP disclosed
CN-114428075-B Ultralow-humidity visual detection material and preparation method and application thereof 吉林大学 2023-08-11 CN disclosed
WO-2023026050-A1 AZETIDINE SUBSTITUTED ROSAMINES USEFUL FOR STAINING MITOCHONDRIA TOCRIS COOKSON LIMITED (GB) 2023-03-02 WO disclosed
WO-2023275537-A1 ANTIMICROBIAL PEPTIDES AND THEIR USE THE UNIVERSITY OF MANCHESTER (GB) 2023-01-05 WO disclosed
CN-114428075-A Ultralow-humidity visual detection material and preparation method and application thereof 吉林大学 2022-05-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240299591-A1 Antimicrobial Peptides and Their Use VIP, FPR1, FPR2 MAOA 2253/4885MAOB 2088/4885GAA 1424/4885
US-20250024837-A1 PESTICIDE SYSTEM ACHE, PFAS, FPGS MAOA 210/4885MAOB 279/4885GAA 1919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.