SCHEMBL31376540

SCHEMBL31376540

CCOC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)c1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MEN1 O00255 1/20 0.42
S1PR4 O95977 1/20 0.42
S1PR1 P21453 1/20 0.42
MAPK1 P28482 1/20 0.42
SLC5A1 P13866 1/20 0.40
SLC5A2 P31639 1/20 0.40
GAA P10253 2/20 0.40
HTT P42858 1/20 0.38
MMP8 P22894 1/20 0.38
CYP1A2 P05177 2/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4718293 0.89 MAPT (0.45) MAPTKMT2ALMNANPSR1MEN1
SCHEMBL31376548 0.84 CA12 (0.43) MAPTLMNANPSR1GAAHTT
SCHEMBL31376554 0.84 MAPT (0.42) MAPTKMT2ALMNANPSR1MEN1
SCHEMBL31376573 0.84 MMP8 (0.50) MAPTKMT2AMEN1MAPK1GAA
SCHEMBL31376550 0.81 HTT (0.41) MAPTKMT2AMEN1GAAHTT
SCHEMBL898279 0.78 MAPT (0.47) MAPTKMT2ALMNANPSR1MEN1
SCHEMBL20930834 0.78 KMT2A (0.50) MAPTKMT2ALMNANPSR1MEN1
SCHEMBL536847 0.76 MMP8 (0.56) MAPTKMT2ALMNANPSR1MEN1
SCHEMBL11598177 0.76 LMNA (0.49) MAPTKMT2ALMNANPSR1MEN1
SCHEMBL31376567 0.76 ALDH1A1 (0.40) MAPTLMNANPSR1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250065315-A1 IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES Laboratory for Synthetic Chemistry and Chemical Biology Limited (CN) 2025-02-27 US disclosed
EP-4491270-A1 IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES The University of Hong Kong (HK) 2025-01-15 EP disclosed
CN-119306769-A Iron complexes for enantioselective cis dihydroxylation of olefins 香港大学 2025-01-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250065315-A1 IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES SQLE, NFE2L2, FECH MAPT 366/4885KMT2A 1605/4885LMNA 4197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.