Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2328371 | 0.88 | NFKB1 (0.50) | PELI1MAPTHDAC1HDAC8HDAC6 | |
| SCHEMBL27680047 | 0.86 | MAPT (0.61) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL28087042 | 0.86 | MAPT (0.61) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL649508 | 0.86 | MAPT (0.67) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL3239009 | 0.86 | MAPT (0.67) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL20303734 | 0.86 | MAPT (0.67) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL20303732 | 0.86 | MAPT (0.67) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL159753 | 0.86 | MAPT (0.67) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL7167807 | 0.84 | PLIN1 (0.72) | TRPA1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL10919259 | 0.84 | HCAR2 (0.72) | TRPA1MAPTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219559-A | Cis-enamide-pyrazole derivative and application thereof in anti-inflammatory drugs | 广东省科学院动物研究所 | 2024-12-31 | — | — | CN | disclosed |