SCHEMBL31380901

SCHEMBL31380901

CCOC(=O)c1cc2cc(-c3cnc4ccccn34)ccc2[nH]1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP13 P45452 12/20 0.62
▸ MMP2 P08253 7/20 0.62
▸ MMP14 P50281 5/20 0.62
▸ KDM4E B2RXH2 3/20 0.54
▸ ALDH1A1 P00352 3/20 0.54
▸ HPGD P15428 3/20 0.54
▸ RAB9A P51151 3/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ NPC1 O15118 2/20 0.54
▸ LMNA P02545 2/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ GLA P06280 1/20 0.54
▸ GAA P10253 1/20 0.54
▸ MAPT P10636 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ ATM Q13315 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.52
▸ HTT P42858 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ HRH3 Q9Y5N1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5618409 0.78 MMP13 (0.57) MMP13MMP2MMP14KDM4EALDH1A1
SCHEMBL419130 0.77 MMP13 (0.77) MMP13MMP2MMP14KDM4EALDH1A1
SCHEMBL15642502 0.73 MMP13 (1.00) MMP13MMP2MMP14KDM4EALDH1A1
SCHEMBL25024764 0.73 MMP13 (0.78) MMP13MMP2MMP14KDM4EALDH1A1
SCHEMBL15642864 0.72 MMP13 (1.00) MMP13MMP2MMP14KDM4EALDH1A1
SCHEMBL5567460 0.71 KDM4E (1.00) MMP13MMP2MMP14KDM4EALDH1A1
SCHEMBL5745913 0.71 KDM4E (0.62) MMP13MMP2MMP14KDM4EALDH1A1
SCHEMBL29580772 0.71 KDM4E (0.78) MMP13MMP2MMP14KDM4EALDH1A1
SCHEMBL42002 0.71 KDM4E (0.78) MMP13MMP2MMP14KDM4EALDH1A1
SCHEMBL3500194 0.71 MMP13 (0.75) MMP13MMP2MMP14KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070905-A1 Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity UNIV DE VELENCIA (ES) 2026-03-12 — — US claimed
WO-2025003545-A1 DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE WITH ANTI-INFLAMMATORY ACTIVITY UNIVERSITAT DE VALÈNCIA (ES) 2025-01-02 — — WO claimed
US-20260070905-A1 Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity UNIV DE VELENCIA (ES) 2026-03-12 — — US disclosed
WO-2025003545-A1 DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE WITH ANTI-INFLAMMATORY ACTIVITY UNIVERSITAT DE VALÈNCIA (ES) 2025-01-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070905-A1 Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity IL1A, IL6, IL1B MMP13 178/4885MMP2 350/4885MMP14 1206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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