Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 7/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.65 |
| ▸ | ITGAL | P20701 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | ADK | P55263 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL6254730 | 0.85 | AHR (0.65) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL26612366 | 0.85 | AHR (0.65) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL28087845 | 0.84 | AHR (0.77) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL28241238 | 0.82 | AHR (0.74) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL2059954 | 0.82 | AHR (0.74) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL5317626 | 0.81 | AHR (0.61) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL10370373 | 0.81 | AHR (0.90) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL10761451 | 0.81 | AHR (0.90) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL1160186 | 0.81 | AHR (1.00) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL698 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185288-A1 | THERAPEUTIC AGENTS AND USES THEREOF | Ankh Life Sciences Limited (IE) | 2023-05-31 | — | — | EP | disclosed |
| US-20220033417-A1 | THERAPEUTIC AGENTS AND USES THEREOF | ANKH LIFE SCIENCES LIMITED (IE) | 2022-02-03 | — | — | US | disclosed |
| CN-113214247-A | Azaindole derivative marrow cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-109071533-B | Halogenated allylamine indole and azaindole derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-109071533-B | Halogenated allylamine indole and azaindole derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-109071533-A | Halogenated allylamine indoles and 7-azaindole derivatives inhibitor of lysyloxidase and application thereof | 法玛西斯有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-109071533-A | Halogenated allylamine indoles and 7-azaindole derivatives inhibitor of lysyloxidase and application thereof | 法玛西斯有限公司 | 2018-12-21 | — | — | CN | disclosed |
| US-20100210640-A1 | BENZAMIDE DERIVATIVES, THEIR PREPARATION AND USES IN MEDICINE THEREOF | JIANGSU HENGRUI MEDICINE CO. LTD. (CN) | 2010-08-19 | — | — | US | disclosed |
| EP-2189451-A1 | BENZAMIDE DERIVATIVES, THEIR PREPARATION AND USES IN MEDICINE THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2010-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210640-A1 | BENZAMIDE DERIVATIVES, THEIR PREPARATION AND USES IN MEDICINE THEREOF | HTR4, HTR5A, TPH1 | AHR 1136/4885TRPA1 128/4885CA1 4655/4885 |
| US-20220033417-A1 | THERAPEUTIC AGENTS AND USES THEREOF | MCL1, BCL9, RNASE1 | AHR 1187/4885TRPA1 3798/4885CA1 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.