SCHEMBL31386176

SCHEMBL31386176

Cc1c[nH]c2cc(F)c(Br)c(F)c12

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GPR84 Q9NQS5 4/20 0.35
▸ ATM Q13315 1/20 0.31
▸ REN P00797 1/20 0.30
▸ FFAR1 O14842 1/20 0.30
▸ TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22438703 0.77 GPR84 (0.45) GPR84FFAR1TRPA1
SCHEMBL31748699 0.76 GPR84 (0.34) GPR84
SCHEMBL17452532 0.75 EGFR (0.36) GPR84TRPA1
SCHEMBL31748517 0.74 CHUK (0.38) GPR84
SCHEMBL15300768 0.74 CYP2A6 (0.46) GPR84
SCHEMBL25927666 0.74 GPR84 (0.36) GPR84
SCHEMBL25331893 0.73 PRKAG1 (0.50) —
SCHEMBL31386148 0.72 HTR6 (0.49) GPR84ATMFFAR1
SCHEMBL17175424 0.71 PRKAB2 (0.30) —
SCHEMBL31748637 0.71 GPR84 (0.31) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727591-A1 SMARCA2 DEGRADERS AND USES THEREOF Astrazeneca AB (SE) 2026-04-22 — — EP disclosed
WO-2024256988-A1 SMARCA2 DEGRADERS AND USES THEREOF ASTRAZENECA AB (SE) 2024-12-19 — — WO disclosed
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