Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | HTR7 | P34969 | 4/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727225 | 0.82 | GPR84 (0.41) | HTR6HTR1AHTR7GPR84ATM | |
| SCHEMBL31386055 | 0.80 | ATM (0.38) | HTR6HTR1AHTR7GPR84ATM | |
| SCHEMBL12588447 | 0.78 | P2RX7 (0.40) | HTR6HTR1AHTR7GPR84ATM | |
| SCHEMBL16729373 | 0.78 | GPR84 (0.36) | HTR6HTR1AHTR7GPR84ATM | |
| SCHEMBL16727226 | 0.77 | HTR6 (0.49) | HTR6HTR1AHTR7GPR84ATM | |
| SCHEMBL16065320 | 0.77 | GPR84 (0.38) | HTR6HTR1AHTR7GPR84ATM | |
| SCHEMBL1470845 | 0.77 | HTR6 (0.49) | HTR6HTR1AHTR7GPR84HTR2A | |
| SCHEMBL22438849 | 0.77 | HTR6 (0.46) | HTR6HTR1AHTR7GPR84HTR2A | |
| SCHEMBL4418345 | 0.76 | ATM (0.48) | HTR6GPR84ATMHTR2AHTR1D | |
| SCHEMBL17452499 | 0.74 | HTR1A (0.56) | HTR6HTR1AHTR7GPR84HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727591-A1 | SMARCA2 DEGRADERS AND USES THEREOF | Astrazeneca AB (SE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256988-A1 | SMARCA2 DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2024-12-19 | — | — | WO | disclosed |