Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31387736 | 0.82 | CXCL8 (0.39) | CXCL8APPEPHX1 | |
| SCHEMBL22483860 | 0.77 | EIF4A3 (0.33) | — | |
| SCHEMBL21996264 | 0.70 | DGAT1 (0.47) | — | |
| SCHEMBL22289631 | 0.70 | MDM2 (0.43) | CXCL8APP | |
| SCHEMBL18839300 | 0.70 | DGAT1 (0.51) | APPEPHX1 | |
| SCHEMBL4685960 | 0.68 | CXCL8 (0.47) | CXCL8EPHX1 | |
| SCHEMBL1822227 | 0.68 | GAA (0.49) | CXCL8APP | |
| SCHEMBL26050842 | 0.67 | CYP1A2 (0.46) | — | |
| SCHEMBL31387656 | 0.67 | ICMT (0.35) | — | |
| SCHEMBL12533352 | 0.66 | P2RX7 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513050-B | Heterocyclic compounds which inhibit SHP2 activity | 大鹏药品工业株式会社 | 2024-12-20 | — | — | CN | disclosed |